Which condition is suggested by a family member experiencing blood in urine and flank pain?

The presence of blood in urine, also known as hematuria, combined with flank pain can suggest a serious underlying condition. Renal carcinoma, a type of kidney cancer, often presents with these symptoms. Hematuria occurs when the tumor invades blood vessels, leading to bleeding. Flank pain may result from the tumor pressing on organs or nerves in the area.

The other options, while they may involve hematuria or pain, typically have different clinical presentations or additional symptoms. Kidney stones can cause flank pain and hematuria, but they usually also involve severe colicky pain and can result in blocking urine flow. Bladder infections often lead to hematuria but more commonly present with dysuria or urgency rather than flank pain. Nephrotic syndrome is characterized by significant proteinuria, including edema and changes in blood levels, but it doesn't typically present with hematuria or flank pain.

Thus, renal carcinoma is a leading consideration given the combination of flank pain and blood in urine, which warrants further investigation to confirm the diagnosis and initiate appropriate treatment.